Metyltetraprole is a quinone outside inhibitor fungicide sold under the brand name Pavecto by its inventor, Sumitomo Chemical.
[3] Metyltetraprole is highly effective against Alternaria triticina.
[1] Developed because of increasing resistance to the main group of QoIs.
It does not suffer cross-resistance with the resistance against 11 conferred by the cytochrome b mutation G143A.
[2] The structure of the tetrazolinone pharmacophore is very similar to the triazolone pharmacophore of an inhibitor developed by AgoEva, for which the binding mode has been elucidated in the structure deposited as 3L73 in the protein databank.