It runs along 16.6 km (10.3 mi) on the Independencia roadway and the Gobernador Curiel Avenue from the southern terminus, Fray Angélico, north to Mirador, with a total of 27 stations.

Its main stations, not including the terminals, are: Construction of this line began in April 2008 and was completed in a record time of one year on March 10, 2009.

[3] The Mi Macro Calzada fleet is composed of high-floor articulated buses of the Volvo brand, very similar to those used by the Metrobús BRT system from Mexico City.

In February 2008, there were 130 bus routes that moved through Independencia roadway and Gobernador Curiel Avenue, serviced by more than 2000 buses.

Since September 17, 2014, the service was extended until the Mirador station, spanning 5 more stations, which are: Clemente Orozco, Circunvalación, San Patricio, Independencia Norte and Mirador; the objective being to offload the Parador Service during peak hours, as well as reducing the travel time almost in half.

Like in this example: Juan Álvarez | Alameda | San Juan de Dios | Bicentenario | La Paz | Héroes de Nacozari | Lázaro Cárdenas | Esculturas | Fray Angélico The Niños Héroes station did not provide this service; nevertheless, the route was modified to include it, reducing the stops and travel time for the users of this station.