He played college football for the Iowa Hawkeyes, and was selected by the Green Bay Packers in the fifth round of the 2013 NFL draft.

After four years in Green Bay, Hyde signed with the Bills, where he would form one half of an effective safety tandem with Jordan Poyer.

[5] Hyde ultimately decided to play for the Iowa Hawkeyes and competed mainly on special teams and on a defense that had 11 players who would go on to be drafted into the NFL.

[1] He was moved back to cornerback against Pittsburgh and had two interceptions, the second winning the game for the Hawkeyes as it allowed them to run the clock out.

[8] In his final year with the Hawkeyes, Hyde was named a first-team All-Big Ten selection and also won the Tatum-Woodson Award, annually given to the best defensive back in the conference.

[16] It was speculated by draft analysts and media members that his fall from the fifth round was in part due to his past arrest (see Personal life).

[18] Throughout training camp, Hyde competed to be a backup cornerback against Casey Hayward, Davon House, Jarrett Bush, and James Nixon.

[19] Head coach Mike McCarthy named Hyde the fifth cornerback on the Packers' depth chart to start the regular season, behind Sam Shields, Tramon Williams, Casey Hayward, and Davon House.

[24] In Week 5, Hyde returned the first punt of his career for a two-yard gain before being tackled by Don Carey in the third quarter of the Packers' 22–9 win against the Detroit Lions.

[25] On October 13, 2013, Hyde recorded a season-high seven combined tackles and made his first career sack on quarterback Joe Flacco during a 19–17 victory at the Baltimore Ravens in Week 6.

[27] On December 22, 2013, Hyde earned his first career start and recorded six combined tackles during a 38–31 loss to the Pittsburgh Steelers in Week 16.

Hyde finished his rookie season with 55 combined tackles (41 solo), two pass deflections, and a sack in 16 games and three starts.

Head coach Mike McCarthy opted to change his position due to the Packers lack of depth at safety after the departure of M. D. Jennings to the Chicago Bears in free agency.

In Week 10, Hyde made a season-high two pass deflections, a tackle, and his first career interception in the Packers' 55–14 victory against the Bears.

[34] His interception occurred in the first quarter off a pass by quarterback Jay Cutler and was originally intended for tight end Martellus Bennett.

[35] On November 16, 2014, Hyde collected four solo tackles, broke up a pass, and returned a punt by Donnie Jones for a 75-yard touchdown during a 53–20 victory against the Philadelphia Eagles.

[42] On October 18, 2015, Hyde recorded a season-high nine combined tackles and a pass deflection during a 27–20 victory against the San Diego Chargers.

On January 10, 2016, Hyde made eight combined tackles and a pass deflection in the Packers' 35–18 victory at the Washington Redskins in the NFC Wildcard Game.

On January 8, 2017, Hyde made seven combined tackles and a pass deflection during a 36–13 victory against the New York Giants in the NFC Wildcard Game.

Packers' general manager Ted Thompson neglected to make Hyde a contract offer and later apologized for not being able to work out a deal.

[56] On December 3, 2017, he collected a career-high 12 combined tackles (ten solo) and a pass deflection during a 23–3 loss to the New England Patriots in Week 13.

[58] Hyde and Poyer were one of the highest graded safety duos in 2017 and were considered as possibly the best tandem in the league by many NFL analysts and media members.

On January 7, 2018, Hyde recorded four solo tackles before exiting the Bills' 10–3 loss at the Jacksonville Jaguars in the fourth quarter after sustaining a concussion.

[65] In Week 13 against the 49ers on Monday Night Football, Hyde recorded a team high 12 tackles and his first interception of the season off a pass thrown by Nick Mullens during the 34–24 win.

[73] Hyde has an older brother named Marcus who played safety for Michigan State's football team from 2006 to 2010.

[74] On October 5, 2012, Hyde was arrested for public intoxication and interference with official acts by the Iowa City Police Department.

It was reported that Hyde and a group of 15 people declined to leave Old Capitol Brew Works after staff asked multiple times around closing.

After Iowa City Police arrived, Hyde and a group of friends were pointed out by staff as some of the subjects involved in the disturbance.