He played college football at Rutgers, and was selected by the Detroit Lions in the fifth round of the 2015 NFL draft.

He has also played for the Chicago Bears, New Orleans Saints, Washington Redskins, Kansas City Chiefs and Denver Broncos.

[9] He entered training camp competing with Emil Igwenagu to be the Detroit Lions' starting fullback.

[10] He made his professional regular season debut and first career start in the Lions' season-opener against the San Diego Chargers.

[11] The next game, Burton had his first career carry for a two-yard gain in a 16–26 loss to the Minnesota Vikings.

Although he appeared in 15 games, he wasn't credited with an official start in any of them and also did not receive any carries or receptions throughout his second year.

[18] On September 10, 2017, in his Bears debut, Burton had one rush for seven yards in the 23–17 home loss to the Atlanta Falcons at Soldier Field.

[31] In the Chiefs week 15 game against the Chargers, he scored his first career rushing touchdown on a seven-yard run.

[33] On March 21, 2022, Burton re-signed with the Chiefs on a one-year deal for an undisclosed amount.

[35] Burton won Super Bowl LVII when the Chiefs defeated the Philadelphia Eagles 38–35.