Michael Nip Hall (born 12 June 1953) is an American-Swiss molecular biologist and professor at the Biozentrum of the University of Basel, Switzerland.
[4][5] Hall entered the University of North Carolina at Chapel Hill as an arts major, but switched to zoology as he wanted to study medicine,[5] earning his BSc in 1976.
[5] He then joined Ira Herskowitz's group at the University of California, San Francisco as a postdoctoral fellow.
In 1991, Hall seminally discovered two genes that, when mutated, made rapamycin unable to inhibit cell growth in yeasts.
[12] The gene and the protein it encodes are later renamed the "mechanistic target of rapamycin", while the short form remains mTOR.
[16] Hall also identified many roles of mTORC1 and mTORC2, including ribosomes physically interact with and activate mTORC2,[17] glutamine breakdown stimulates mTORC1,[18] and mTORC2 promotes lipid synthesis and cancer.