The Detroit Science Center operated until 1999 when it closed for construction on a $30 million renovation and expansion - tripling the available exhibit space and adding new theater and performance areas.
The Detroit Science Center had a grand re-opening celebration in July 2001 and continued to expand, adding a new Digital Dome Planetarium in December 2001 and a 4D Toyota Engineering Theater in 2008.
In partnership with the Thompson Educational Foundation, the Detroit Science Center embarked in April 2008 on another expansion of 80,000 sq ft (7,400 m2).
The school facility has classrooms, a gymnasium with locker rooms, food service, and offices, and shares conference space and lobby with the Detroit Science Center.
On September 7, 2012, local Detroit news reports indicated that a new organization, the Michigan Science Center, would open and operate the facility.