Michwacho Lake is a freshwater body crossed by the Chibougamau River, in the southern part of Eeyou Istchee James Bay (municipality), in the administrative region of Nord-du-Québec, in Quebec, Canada.

The surface of Michwacho Lake is usually frozen from early November to mid-May, however, safe ice movement is generally from mid-November to mid-April.

A bay of the lake stretches out on the Southwest to the foot of Mount Michwacho with a peak of 538 metres (1,765 ft).

Another connected bay on the north side stretches westward on 1.1 kilometres (0.68 mi) to the foot of Mount Roy, whose summit reaches 498 metres (1,634 ft).

The toponym "Lake Michwacho" was formalized on December 5, 1968, by the Commission de toponymie du Québec when it was created.