[citation needed] In 1977, Mike regularly visited the set of The Muppet Show with his homemade puppets, eventually meeting Jim Henson.

[citation needed] After leaving school in 1980, Quinn joined The Jim Henson Company and worked on the 1981 film The Great Muppet Caper puppeteering in crowd scenes and acting as a double for various main Muppet characters.

Quinn later designed and built the Podlings for The Dark Crystal, where he also performed the Skeksis Slave Master SkekNa (who was voiced by David Buck).

Quinn joined George Lucas's Industrial Light and Magic as an animator, first working on Jurassic Park III and then Star Wars: Episode II – Attack of the Clones.

In 2018, Quinn provided the voice of the Stan Laurel-based character Agnes Packard in the Cartoon Network series, Mighty Magiswords opposing Ken Mitchroney voicing her Oliver Hardy-based husband Mr. Pachydermus in the episode "Pachydermus Packard and the Camp of Fantasy".