Mikheil’s mother, Nineli Janelidze (maiden name: Shengelia), a medical doctor, served as a director of neonatology department at the maternity hospital in Kutaisi.

In 2008, Mikheil commenced the Dual MBA program of Grenoble Ecole de Management, France and Caucasus School of Business, Georgia.

Mikheil was on the government's task-force responsible for the preparation of Georgia for the Deep and Comprehensive Free Trade Area (DCFTA) agreement with the European Union.

[7] Janelidze successfully concluded negotiations with the European Union on the DCFTA and initialled the agreement at the Eastern Partnership Summit (EaP) in Vilnius on 28 November 2013.

[16] In 2017 and 2018, record number of UN Members voted in favor of the United Nations General Assembly resolution reiterating the right of return of all displaced persons and refugees to Georgia’s Abkhazia and Tskhinvali Region/South Ossetia.

[18] In 2016, the Committee of Ministers' Deputies of the Council of Europe with absolute majority adopted a decision, which, first time, emphasized the responsibility of Russia as a state exercising effective control over Georgia’s occupied territories to ensure the protection of human rights there.

[19] For the first time since the Russia-Georgia war in August 2008, a special group within the Organization for Security and Cooperation in Europe (OSCE) adopted a declaration on the conflict that supports Georgia's territorial integrity and condemned the occupation of Georgian soil.

In 2016, during the 35th round of the Geneva International Discussions, the agreement was reached on the resumption of meetings of the Incident Prevention and Response Mechanism in Gali (IPRM), Abkhazia region.

"The package of proposals adopted today by the Government of Georgia can benefit the citizens living on both sides of the Administrative Boundary Lines by facilitating trade, education and mobility," said the EU spokesperson in a statement issued on 4 April.

However, we should also look at the costs of unnecessary and hardly justified delays in making decisions to honor mutual commitments," Janelidze stated at the Conference ‘Visa Liberalization as an EU Foreign Policy Tool’ in Brussels on 1 December 2016.

[28] After the active negotiations with the different stakeholders in the EU and its member states, Georgia achieved a visa-free travel arrangement with the European Union for Georgian citizens in March 2017.

[39] In December 2017, Janelidze participated in another NATO-Georgia Commission meeting held in Brussels, which was described as "very constructive” by NATO’s Secretary General Jens Stoltenberg.

"Deepening cooperation with the United States, our main strategic partner, is a highly important issue for the government and Foreign Ministry," Janelidze said.

[46] In February 2017, at the meeting in DC,[47] a top diplomat of the Trump administration, Tillerson, assured Janelidze in a 'full support' of U.S. in standoff with Russia over breakaway regions.

We look forward to establishing a strong legal framework after Brexit including developing free trade and trade-economic cooperation”, Minister Janelidze said at the meeting in London with the U.K. Secretary of State Boris Johnson.

Highlighting the opportunities of further deepening co-operation in the areas of infrastructure, energy and green technologies, the two ministers spoke about the Belgian business delegation’s upcoming visit to Georgia.

In 2017, he hosted in Tbilisi the fifth ministerial between Foreign Ministers, where the three officials agreed to intensify trilateral cooperation and develop the region’s energy, transport and Silk Road potential.

This issue he discussed in Kazakhstan with his counterpart, Abdrakhmanov, who stated that Kazakhstan attaches "great importance to improving the existing and creating new trade and transport routes and economic corridors that connect the countries of Central Asia, South Caucasus, Europe and the Persian Gulf, as well as maximizing the use of the Trans-Caspian International Transport Route.

[72] "To expand further regional transport and trade ties, connecting the Rasht-Astara railway to the Baku-Tbilisi-Kars line as well as developing a transit corridor to link the Indian Ocean to Europe, first ever quadrilateral meeting of the Foreign Ministers of Azerbaijan, Georgia, Iran and Turkey was held in Baku in 2018.

"Today, among other things, we talked about possibilities to use these differences to strengthen our cooperation and for joint projects”, Janelidze stated during his official visit in Yerevan.

“This Document is a proof of the unanimous will of the four countries to achieve greater results, through joint efforts, to the common benefit of their people,” - stated Janelidze.

During the visit agreement was reached to simplify visa procedures for Georgian citizens as well as to promote Georgia among Japanese tourists so that the two countries develop close people-to-people connections.

At the meeting with the Indonesian Industry Minister Airlangga Hartarto in Davos in 2018, Janelidze stated about the Georgia’s priority to further develop trade-economic ties with South-East Asia – "being one of the rapid growing economy in the world.

[81] Georgia’s Permanent Representative to United Nations (UN) Kaha Imnadze has been appointed as co-chair of the intergovernmental negotiations on UN Security Council reform.

[82] Georgia took leadership on SDG 16, to promote and share experiences on good governance, rule of law and anti-corruption policies on a multilateral level.

Janelidze hosted and delivered a speech at the 16+ Forum Inaugural Annual Showcase "From Words to Action: Implementing SDG 16+ at the local and national level" held in Tbilisi, Georgia, with 150 representatives from 25 countries.

In 2016 Qvevri, a large, ancient Georgian winemaking vessel was placed in the courtyard of the United Nations (UN) Geneva office to mark the organisation’s 70th anniversary.

Janelidze delivered a speech at the ceremony underlining the importance of TSU in building Georgian democracy and the need to rethink the current education system to catch up with the Fourth Industrial Revolution.

[89] Janelidze spoke at the roundtable conference titled “Cooperation for Prosperity – a Strategy for Future Centennial” together with 20 high-level delegations, including the Presidents of Armenia, Finland, Latvia, Lithuania, Poland, Slovakia and the European Commission.

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