Mikro Souli (Greek: Μικρό Σούλι) is a semi-mountainous village (altitude 300 m.) in Serres regional unit of Central Macedonia, Greece, located 60 km southeast of the city of Serres.

Its former name was "Semalto" (probably from the Latin words "semi-" and "altus") A little further west of Mikro Souli, on the hill "Zavarnikia", were revealed traces of an ancient settlement, which was located on the via Egnatia, as presumed by the discovery of a Roman miliarium.

[2] On the next hill of "Agia Marina" there was a prehistoric settlement.

Thus, taking also into account the ruins of early Christian basilicas, it is concluded that the area of these two hills was continuously inhabited from prehistoric to Byzantine times.

[3] This Central Macedonia location article is a stub.