Minaprine (INN, USAN, BAN; brand names Brantur, Cantor) is a monoamine oxidase inhibitor antidepressant drug that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions.

[2][3] A study found that it acts as a reversible inhibitor of MAO-A (RIMA) in rats.

[4] It has also been found to weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.

[7] The final step is the reaction between a chloro-substituted pyridazine and the primary amine group of a morpholine derivative.

[7][8] The required pyridazine can be made by the reaction of acetophenone and pyruvic acid, followed by ring formation using hydrazine, giving a pyrazidinone.