Mindanao Avenue (Filipino: Abenida Mindanao) is an eight-to-ten-lane divided avenue connecting EDSA and NLEX and is a part of Circumferential Road 5 (C-5) in Metro Manila, Philippines.

[citation needed] Another road in Quezon City, also named Mindanao Avenue, starts in Barangay Santa Monica, crosses Commonwealth Avenue and Regalado Highway, and terminates at a dead end at the School of Saint Anthony in Barangay Greater Lagro, Quezon City.

In 2017, DPWH resumed construction of the 3.2-kilometer (2.0 mi) Mindanao Avenue Extension Project after it had been halted for years due to road right-of-way issues, notably involving residential areas.

In June 2018, DPWH opened an additional 700-meter (2,300 ft) portion from P. Dela Cruz Street to the current end at MGM Road.

[6] The road will be extended until it meets General Luis Street in North Caloocan.