The Quirino Highway, formerly called the El Quirino Express Road[citation needed] or Ipo Road, is a four-to-eight lane, secondary highway that connects Quezon City to the municipality of Norzagaray in Bulacan, Philippines.

[8] It was later changed to the Don Tomas Susano Road, after the first officially recognized political leader of the district and municipal president of Caloocan during the American occupation of the Philippines.

Quirino Highway starts from Epifanio de los Santos Avenue, near the Balintawak Cloverleaf in Quezon City.

It then runs shortly in parallel to North Luzon Expressway (NLEX) carrying one-way northbound traffic and turns northeast towards the northwestern part of Quezon City.

Crossing the Marilao River, it then enters the province of Bulacan at San Jose del Monte, straddling along the mountainous terrain, and ends at the roundabout with Villarama Road and Ipo Road in Bigte, Norzagaray.