Both the largest (128,473 km²) and the penultimate of the least populated, the regional county municipality of Minganie extends from Labrador to the middle of the Honguedo Strait in the St. Lawrence River and includes the hinterland of Le Golfe-du-Saint-Laurent RCM and Anticosti Island.

It has an area of 63,731.31 square kilometres (24,606.80 sq mi) according to Quebec's Ministère des Affaires municipales, des Régions et de l'Occupation du territoire (which includes coastal, lake, and river water territory),[2] or a land area of 53,340.31 square kilometres (20,594.81 sq mi) according to Statistics Canada.

However, it is possible to reach the area by chartering seaplanes that can easily land under favourable atmospheric conditions in many deep bays and on windward waters sheltered by islands.

The high latitude and low altitude, combined with the proximity of the cold currents of Labrador, explain the subarctic vegetation specific to the Minganie.

The entirely calcareous nature of the horizontal stratified rocks, which make up the Anticosti - Minganie, exerts a profound influence on the structure of the flora and on the choice of species.

[18][19] Overwiew of the diversity During the summers of 1964 and 1965, during geological research, Jean Depatie with a team of geologists and students, assisted by 3 canoemen and lumberjacks, plus a cook, explored 440 square miles of a territory stretching from Sept-Îles to Blanc Sablon, in the Lac à l'Ours region.

In the field, scientists noted an abundance of Canadian beavers, a few otters and American mink, many hares, partridges and a multitude of ducks.

[20] The waters of the St. Lawrence Estuary are internationally recognized as a vital feeding ground for rare or common species of marine mammals.