The background of the coordination work of the different areas of governmental action exercised by the current Ministry of the Presidency can be track down in the resolution of 30 November 1714, which, under the reign of Philip V, the Cabinet Council was created.

It is at this time that the embryo of a ministerial coordination function and the Secretariat of the Government can be glimpsed, with the establishment of a book where the agreements of the Council would be written, which fell to the Ministers themselves.

It was also created, the position of the Assistant Secretary of the Presidency of the Council of Ministers, however in its origins had no relationship with the functions of Secretariat of the Government until 1871.

At the beginning of the 1890s, the structure of the Office of the Assistant Secretary of the Presidency was remodeled, assigning functions of relationship with the constitutional bodies and with regard to appointments and dismissals.

It is that time, the figure without especially specific functions, performs tasks as different as those derived from being the Technical Secretariat for Morocco and Colonies and for the National Tourist Board.

Under the Franco regime was confirmed by Decree of 11 August 1939 the existence of the Assistant Secretary of the Presidency, and Luis Carrero Blanco was appointed it.

According to the Law of 22 December 1948, the Office of the Assistant Secretary was a special Department that would be in charge of the General Policy and Coordination services.

In spite of the existence of an entire Office since 1951 at the service of the Minister-Undersecretary of the Presidency (or Minister-Assistant Secretary), the Ministry was officially created by a Law of 2 January 1974.