Mirsaid Mirshakar was the son of a farmer, born in the village of Sindev, Pamir, Russian Empire, now Gorno-Badakhshan Autonomous Province, Tajikistan.

He graduated from the Central Soviet Party School in Dushanbe in 1930, and his works began to appear in print the same year.

He wrote narrative poems glorifying historic events in the life of the Tajik people after the October Revolution.

His writings for children were the subject of the doctoral thesis of literary critic Jonon Bobokalonova.

He also served in a number of administrative positions, including Chairman of the Supreme Soviet of the Tajik SSR.