[2] On October 5, 1931, Clyde Pangborn and co-pilot Hugh Herndon landed in the hills of East Wenatchee, Washington, following a 41-hour flight from Sabishiro Beach, Misawa, Japan, across the northern Pacific.

On a 1932 flight from New York City to Rome for aviation medicine research, she was last sighted by an ocean liner in the eastern Atlantic, before disappearing without a trace.

Clyde Pangborn and Hugh Herndon modified Miss Veedol while being held in Japan – on unfounded suspicions of spying – to be able to carry more fuel, and to be able to jettison the landing gear.

Looking for a worthwhile aviation record to set, they decided to modify Miss Veedol to make the first non-stop trans-Pacific flight, for which the Japanese newspaper Asahi Shimbun had offered a $25,000[14] prize.

[15] Loaded well beyond the manufacturer's maximum operating weight, on October 4, 1931 (Japanese time), Miss Veedol only barely managed to take off from a specially prepared area of Sabishiro Beach.

[15] As Herndon and his mother were the main financial backers of the flight, they kept almost all the Asahi Shimbun prize money and the proceeds of the sale of Miss Veedol.

[17] Miss Veedol was subsequently sold and eventually ended up owned by a group including Dr. Leon Martocci-Pisculli (usually referred to as Pisculli), who recruited pilot William Ulbrich and copilot Gladys Bramhall Wilner (13 August 1910 – 3 July 2009)[20] for a record New York City to Rome flight.

[1] A barnstormer and flight instructor in earlier years, in September 1932, Ulbrich held a transport pilot's licence and had 3,800 hours flying experience.

[26] Wilner died at the age of 98 in Jacksonville, Florida; she was the last surviving person to have ever flown in Miss Veedol (as The American Nurse).

[27] In respect of his second concern, he brought a woodchuck named "Tail Wind" on the flight, as a carbon monoxide detector, due to these animals' sensitivity to the gas.

[1] (Pisculli had found Tail Wind with a broken leg on a road in Westchester County, New York, and had nursed it back to health.

[26]) His more general objective was to encourage physicians and nurses to learn to fly and parachute jump, so that they might put these skills to use in emergency medicine.

[26] The aircraft was subsequently sighted over Cape Cod, Massachusetts, then by the American Oil Co. tanker Winnebago in mid-Atlantic at 5:50 pm EST and lastly by the liner SS France 640 kilometres (400 mi) from its intended landfall in Europe.

In addition to the Miss Veedol replica in the Misawa Aviation and Science Museum, there was a somewhat cruder replica of Miss Veedol on display outdoors on Sabishiro Beach at 40°44′43.8″N 141°24′55.3″E / 40.745500°N 141.415361°E / 40.745500; 141.415361 (Sabishiro Beach) until it was destroyed during the 11 March 2011 tsunami which caused widespread damage in the coastal area of Northeast Honshu.