Mission Sioux Airport (FAA LID: 0V6) was a public use airport located two nautical miles (3.7 km) east of the central business district of Mission, a city in Todd County, South Dakota, United States.

The airport is no longer listed in the Airport/Facility Directory and the runway pavement is badly deteriorated.

Mission Sioux Airport covers an area of 240 acres (97 ha) at an elevation of 2,605 feet (794 m) above mean sea level.

It has one runway designated 11/29 with an asphalt surface measuring 3,200 by 60 feet (975 x 18 m).

[1] For the 12-month period ending June 23, 2009, the airport had 700 general aviation aircraft operations, an average of 58 per month.