The road heads northwest through a mostly wooded area past a few homes before turning to due west.
MS 413 passes the entrance of French Camp Academy, businesses, and the Natchez Trace Parkway.
Heading northwest through forestland, the highway crosses Big Black River and turns to the north.
MS 413 heads past a small farm then enters the town of Kilmichael on River Road.
[2] A state highway connecting the Weir vicinity with Kilmichael by way of French Camp had existed since at least 1932.