The highway heads north on Omega Road crossing Deer Creek at a culvert.

After about 0.7 miles (1.1 km), the highway turns onto Dummy Line Road, again with a dirt surface.

Heading east northeast, the highway crosses Little Sunflower River and enters Delta National Forest.

MS 433 continues into town on Wilson Street before sharply curving to the south onto West Railroad Avenue.

MS 433 continues its northeasterly course through mostly farm fields, passing through the community of Myrlesville before turning north.

[6] By 1960, the route was truncated at its north end at MS 14 near Ebenezer but was extended further south from Holly Bluff to US 61 in southern Sharkey County.