The two-lane road briefly heads west before turning to the north.

At Center Hill, MS 495 passes Center Hill Martin Road which provides access to Okatibbee Dam and its associated park and lake, a gas station, and West Lauderdale Elementary School.

As the road crosses into Kemper County, it heads to a more forested area passing fewer houses and settlements.

MS 495 breaks off the concurrency to head north again through wooded areas but with some farm fields present along the road.

It eventually curves more to the northeast to end at MS 397 south of the community of Preston.