Center Hill, historically Centre Hill, is an unincorporated community in DeSoto County, Mississippi, United States.

It is located east of Olive Branch, Mississippi.

[2] In the January 1, 1857, issue of The Memphis Daily Appeal, there is an announcement from the Secretary of the Board of Trustees, Robert Wilson, that the first classes of the college were to be held on February 21, 1857.

[3] William Carey Crane was the founder, chief promoter,[4] and the president of the college from 1857 to 1860.

[4] Today, there exists the Center Hill Elementary School,[6] Middle School,[7] and High School,[8] the Center Hill Baptist Church,[9] and the Center Hill Baptist Church Cemetery in the area, and they have Olive Branch, Mississippi, addresses.