Mamytov was born on 16 December 1939 in the village of Kök-Jar, Nookat, in the Osh Region of the Kirghiz SSR (modern Kyrgyzstan).

[2] From 1966 to 1971 he completed his clinical residency and postgraduate studies and defended his dissertation on the topic of neurosurgical problems of brain tumors at the A. L. Polenov Leningrad Research Institute of Neurosurgery.

From 1971[2] (or 1972[3]) to 1973 he headed the neurotraumatology department of the Republican Clinical Hospital in Frunze (now Bishkek).

From 1997 to 2002 he was Vice-Rector for research at KSMA; from 2002 to 2005 he was Health Minister of Kyrgyzstan, and from 2002 to 2007, he was Rector of the Asian Medical Institute.

He is an academician and member of the presidium of the Kyrgyz Academy of Sciences,[4] the president of the Kyrgyz Neurosurgical Association, an honorary member of the associations of neurosurgeons of Russia, Kazakhstan and Uzbekistan, and Honored Worker of Science of Kyrgyzstan.