Mithiani (Sindhi: مٺياڻي), (Urdu: مٹہیانی) is a town in the Naushahro Feroze District, of Sindh, Pakistan.

Owing to its strategic position on the Indus River, Mithiani was a transit point for import and export from Afghanistan to Rajputana.

Small ferries would load goods from Mithiani to Paat Sharif, a historic town on left bank, in Dadu district During the British era, the local Hindu community opened first English medium school in the first half of the 20th century as they were more open to secular education than Muslim population, who were more inclined toward religious education.

The town of Mithiani is also home to hundreds of immigrants from India during the period of partition.

Wheat, Sugarcane, Seseme seeds and lentils are the main crops grown in Mithiani town.

In olden days, people would go to Naushahro Feroze or Moro for shopping but now every possible daily life items are available in Mithiani, from clothes to household utensils.

However, there is no institution for higher education therefore boys as well as girls are sent to other neighbouring cities to get certification onward matriculation.

During 1999, status of Government Elementary College Mithiani was upgraded after got registered and approved from HEC.

Government Boys High School Mithiani was affiliated with the Sukkur Board since long period of time till 2019.

[4] The private school is run by a very experienced retired teacher, Ghulam Siddique Pathan.