Mkalama District is one of the six districts of the Singida Region of Tanzania.

[1] Mkalama District is bordered to the north by Simiyu Region and Arusha Region, to the east by Manyara Region, to the south by Singida Rural District and to the west by Iramba District.

According to the 2012 Tanzania National Census, the population of Mkalama District was 255,514.

[2][3] Paved trunk road T3 from Morogoro to the Rwandan border passes through a small portion of the district.

[4] As of 2012, Mkalama District was administratively divided into 14 wards.