Arusha Region is home to Ngorongoro Conservation Area, a UNESCO World Heritage Site.

[2] Arusha Region is a tourist destination in Africa and is the hub of the northern Tanzania safari circuit.

Remains of 600-year-old stone structures are found at Engaruka, just off the dirt road between Mto wa Mbu and Lake Natron.

[4] Arusha Region is home to Laetoli and Olduvai Gorge national archaeological sites both locations with discoveries of prehistoric hominids.

[7] In the 1880s a pandemic of rinderpest killed thousands of cattle and forced a large section of the Masai people in the west and integrated into Arusha agriculturally based society.

[9] Johannes then decided to conduct the scorched earth doctrine on the WaArusha people, leading to a famine and collapse of Arusha society.

[10] For various reasons, many of the white settlers moved to Kenyan highlands or back to South Africa in a few years before the advent of World War I.

The administrative region of Arusha existed in 1922[12] while mainland Tanzania was a British mandate under the League of Nations and known as Tanganyika.

In 1948, the area was in the Northern Province, and [13] shortly afterwards, the British appointed the first WaArusha community leader Chief Simeon Laiseri in 1948.

Oldonyo Lengai (Mountain of God in the Maasai language) is an active volcano to the north of the Ngorongoro Conservation Area.

[20] Nyama Choma, the northern Tanzanian barbecue, is a popular dish among some communities in the Arusha Region, particularly the Maasai.

The A-104 runs northward, to the west of Mount Meru, from Arusha to Longido and Namanga at the Kenyan border before continuing to Nairobi.

The A-104 also runs westward past Monduli to its junction at Makuyuni with the B-144 road that leads to Mto wa Mbu and the Ngorongoro Conservation Area.