The Mohawk River is the largest tributary of the McKenzie River,[2] approximately 30 miles (48 km) long, in west central Oregon in the United States.

It drains part of the foothills of the Cascade Range on the southeast end of the Willamette Valley northeast of Springfield.

It rises in northern Lane County, approximately 12 miles (19 km) northeast of Springfield.

[4] Spores was a native of the Mohawk River region of New York, and the Oregon river's valley reminded him of the Mohawk Valley in his home state.

Named tributaries from source to mouth are North Fork Mohawk River and South Fork Mohawk River followed by Log, Bette, Drury, Shotgun, Polly, Mill, and Cartwright creeks.