[5] As of 2020, the Mondrian brand of hotels, including its flagship in Los Angeles, is managed by Accor's lifestyle subsidiary Ennismore.

[6] On December 4, 2007, rapper Pimp C was found dead in his room at the Mondrian Hotel in West Hollywood, California.

One of the main characters in William Gibson's novel Spook Country (2007) stays on business at the Mondrian while in Los Angeles.

The lyrics to 50 Cent's song "Places to Go," from 8 Mile: Music from and Inspired by the Motion Picture (2002) reference the hotel: "Matter of fact you gotta send it to Sunset Blvd up in the Mondrian"[citation needed] Several episodes of the HBO series Entourage were filmed on-location at the Mondrian.

[citation needed] In the third installment of the Family Guy's Star Wars parody, "Episode VI It's a trap," about 16:11 into the episode, the character played by Angela thanks her audience for meeting her "in the lobby of the Mondrian," drawing a comparison between the Mondrian Miami lobby's futuristic design and the interior of a Star Wars spaceship.