Monluè is a district ("quartiere") of Milan, Italy, part of the Zone 4 administrative division, located east of the city centre.

As a consequence of its isolation from the city proper, it has maintained wide green areas (the most notable of which is Monluè Park) and the general appearance of a small country town.

A distinct rural settlement in Monluè is reported at least since the Middle Ages; it was originally called Mons Luparium (in Latin, meaning "mountain - or hill - of the wolves").

This toponymy suggests that, back then, the area was probably more hilly than it is today, and that the forests between Monluè and Milan used to be infested by wolves.

In the early 20th century, the Monluè complex was ceded to the Pio Albergo Trivulzio (a humanitarian Milanese institution).