[6] As of the census[12] of 2010, there were 41,276 people, 16,484 households, and 11,461 families residing in the county.

25.80% of all households were made up of individuals, and 12.00% had someone living alone who was 65 years of age or older.

The county has leaned Republican ever since 1920; although before this, it did tend to vote Democratic between 1896 and 1916 except during the landslide loss of Alton B. Parker in 1904.

The last Democratic Senatorial candidate it backed was Ben Nighthorse Campbell, who later shifted to the Republican Party, in the 1992 election.

[15] Montrose County did back Constitution Party nominee Tom Tancredo in the 2010 gubernatorial election,[16] and Bill Ritter did win 46 percent in 2006,[17] but Roy Romer in 1990 remains the last Democratic candidate for governor to win Montrose County.