Moon Lake is an unincorporated community located in Coahoma County, Mississippi, United States.

In 1926, the Clarksdale Elks Club built a lodge on Moon Lake.

Tennessee Williams visited Moon Lake Casino, and referred to it in all but two of his plays.

Yes, the three of us drove out to Moon Lake Casino, very drunk and laughing all the way.Sarah Wright, who has owned the property since 1985, stated, "they loved to go to the Moon Lake Casino, because the place served Kansas City steaks and even flew in lobster from Maine, no easy task as airplane travel was then in its infancy.

"[2] William Faulkner also visited the place, and referred to it in one of his novels as "Moon Lake Hotel."