Sunflower Landing is an unincorporated community in Coahoma County, Mississippi, United States.

[3] A commission appointed by Franklin D. Roosevelt in 1935 determined that Sunflower Landing was the "most likely" place where explorer Hernando de Soto and his expedition crossed the Mississippi River in 1541.

It was theorized that de Soto and his men spent a month building flatboats near Sunflower Landing, then crossed the river at night to avoid the Native Americans who were patrolling the river, and with whom de Soto had previously hostile relations.

[4][5] More recent research suggests other Mississippi locations may have also been the site of de Soto's crossing.

[8] In 1942, the United States Army Corps of Engineers removed Sunflower Bend from the course of the Mississippi River.