Moore Creek (French: ruisseau Moore) is a creek in South Algonquin, Nipissing District in Northeastern Ontario, Canada.

[1] Moore Creek begins at Cross Lake at an elevation of 441 metres (1,447 ft) and travels 5 kilometres (3.1 mi) southwest to McKenzie Lake at an elevation of 395 metres (1,296 ft).

The creek then flows north 6.5 kilometres (4.0 mi) towards Moore Lake at an elevation of 380 metres (1,247 ft), taking in the right tributary Coghlan Creek from Coghlan Lake along the way.

Finally, the Moore Creek heads 7 kilometres (4.3 mi) north, passing under Ontario Highway 523, to its mouth at the Madawaska River, at an elevation of 314 metres (1,030 ft).

The creek is entirely in South Algonquin, Nipissing District, but part of the drainage basin, like the southern end of McKenzie Lake and some other tributaries flowing from the south, is in Hastings Highlands, Hastings County.