It borders the municipalities of Calera to the northwest, Pánuco to the northeast, Vetagrande to the east, and the city of Zacatecas to the south.

The highest point of the municipality is Cerro San Gil in the Sierra de Zacatecas southeast of the town of Hacienda Nueva, with an elevation of 2,603 metres (8,540 ft) above sea level.

[6] In pre-Hispanic times, the Morelos area was inhabited by the Cagihua tribe of the Zacateco people.

[8] The municipal government of Morelos comprises a president, a councillor (Spanish: síndico), and ten trustees (regidores), six elected by relative majority and four by proportional representation.

[1] INEGI lists 28 inhabited localities in the municipality,[7] of which two are classified as urban:[11] Economic activities in Morelos include agriculture and small businesses.