The Chicago, Burlington and Quincy Railroad built the pressed brick depot in 1912.

Using funds received under the American Recovery and Reinvestment Act of 2009, Amtrak installed a new wheelchair lift and enclosure at the station in 2010.

[3] The Mount Pleasant station has a waiting area and lobby open to the public 365 days a year.

[4] Mount Pleasant is also served by intercity buses from Burlington Trailways.

However, the intercity bus stop is located 1.8 miles (2.9 km) east of Mount Pleasant station, at the Heidelburg Motel at 2005 East Washington Street.