Mozambique competed at the 2012 Summer Olympics in London, from 27 July to 12 August 2012.

In the weeks before the Games, Mozambique athletes trained at Comberton Village College in Cambridge.

[2] The Mozambique National Olympic Committee (Portuguese: Comité Olímpico Nacional de Moçambique) sent the nation's largest delegation to the Games since the 1992 Summer Olympics in Barcelona.

Track hurdler Kurt Couto, who was considered Mozambique's best medal prospect at the Olympics, reprised his role as the nation's flag bearer for the third consecutive time.

Mozambique, however, again failed to win a single Olympic medal.