Muelle de los Bueyes is a town and a municipality in the South Caribbean Coast Autonomous Region of Nicaragua.

The demand for rubber and hule by American companies in the 1930s integrated it into the Caribbean coast's economy as a supplier of these products, which were transported via the Mico-Escondido River route to Bluefields.

A second major migratory wave, the most intense, occurred from the 1950s to after 1974, linked to the second and third stages of the country's integration into the global market, with cotton and meat as the main agro-export products.

From March to August, it is warmer with temperatures reaching up to 33°C; it is a regularly rainy area for about 9 months of the year, and annual rainfall ranges from 2700 to 2900 mm.

Its most recognized business in the livestock sector is the dairy processor Castilac, commonly known as El Guanaco, which belongs to the Miranda family.