In 1574, Akbar captured the island fortress of Bhakkar as part of his efforts to extend his control over the southern region of Sind near the Indus River's mouth.

This strategic move aimed to solidify his dominance in northwestern India and establish a base for launching an offensive against Kandahar, which was then under the rule of Shah Abbas of Persia.

Following two battles, Mirza Jani Beg was defeated in 1591 and surrendered his territory, including the strategic forts of Thatta and Sehwan.

Consequently, Mughal control expanded to include Bhakkar and Siwistan by the 16th century, while the rest of Sindh was granted to Jani Beg as a jagir.

Despite suffering significant personal losses, including the deaths of his father, Muhammad Paynda, and his son, Abu'l Fath, Jani Beg managed to resist the Mughal advance for two years.