Murrayville is a census-designated place (CDP) in New Hanover County, North Carolina, United States.

According to the United States Census Bureau, the CDP has a total area of 11.5 square miles (29.8 km2), all land.

As of the 2020 United States census, there were 16,582 people, 6,646 households, and 4,370 families residing in the CDP.

As of the census[3] of 2000, there were 7,279 people, 2,896 households, and 2,079 families residing in the CDP.

20.4% of all households were made up of individuals, and 3.2% had someone living alone who was 65 years of age or older.