Myrtle Grove is a census-designated place (CDP) in New Hanover County, North Carolina, United States.

As of the 2020 United States census, there were 11,476 people, 4,172 households, and 3,222 families residing in the CDP.

As of the census[3] of 2000, there were 7,125 people, 2,839 households, and 2,222 families residing in the CDP.

There were 3,021 housing units at an average density of 439.9 per square mile (169.8/km2).

16.3% of all households were made up of individuals, and 4.9% had someone living alone who was 65 years of age or older.