The facility includes four galleries with frequently changing exhibitions, the Discovery House with hands-on activities, live animal habitats, the Mark Smith Planetarium, nature trail, garden, store, auditorium, and classrooms.

[4] Planned additions to the museum, including a bat cave and amphitheater, were approved in March 2019 and are expected to be complete by the end of the year.

Exhibitions shown include Fired by Genius: The Ceramics of Pablo Picasso, Sunlight and Shadow: American Impressionism, and The Art of Tiffany.

This section of the museum includes "Ziggy", a 40 million year old whale fossil,[9] as well as a taxidermy adult polar bear.

The Museum of Arts and Sciences' grounds include an amphitheater, a pavilion, raptor retreat, bat cave, and walking trails.