The Musquaro Lake is located in the unorganized territory of Petit-Mécatina, Quebec, in the Regional County Municipality (MRC) Le Golfe-du-Saint-Laurent Regional County Municipality, in the administrative area of the Côte-Nord (North-Shore), in Quebec, in Canada.

Located on the Côte-Nord (North Shore) of Gulf of Saint Lawrence, the lake Musquaro covers an area of 207 square kilometers.

The term "Musquaro" is a translation adapted from Native American language, meaning "tail of a black bear".

In his writings, the father Charles Arnaud indicates that up the Musquaro River, a mountain having the complete shape of a bear is encountered; and "not even the tail" is missing.

Naskapi uses the label "Maskuanu Shipis" meanings the little river of the "tail of a black bear."