Errors of replication often involve translesion synthesis by a DNA polymerase when it encounters and bypasses a damaged base in the template strand.
[6] Previously, people used the word "sport" (related to spurt) to refer to abnormal specimens.
The word finds its origin in the Latin term mūtant- (stem of mūtāns), which means "to change".
[6] Mutants should not be confused with organisms born with developmental abnormalities, which are caused by errors during morphogenesis.
Epigenetic alterations include methylation of CpG islands of a gene promoter as well as specific chromatin histone modifications.