Mutunópolis is located in the extreme north of the state, 38 km south of the important regional center of Porangatu.

Highway connections from Goiânia are made by GO-080 / Nerópolis / São Francisco de Goiás / BR-153 / Jaraguá / GO-080 / Goianésia / GO-342 / Barro Alto / BR-153 / Uruaçu / Estrela do Norte / GO-241.

Mutunópolis is surrounded by the following municipalities: The origin of this town began in 1950 when the founder, João Gonçalves Pacheco, arrived looking for fertile lands to cultivate.

In 1931 it was elevated to district in the municipality of Porangatu, altering the name to Mutunópolis, city of the "mutum".

The economy was based on modest agriculture, cattle raising, services, public employment, and small transformation industries.

Agricultural production was limited with the main crops being rice, corn, manioc, bananas, and soybeans.