The medical center serves as a clinical site for medical students from Michigan State University - College of Human Medicine, Central Michigan University, and MidMichigan Community College nursing students.

A family medicine residency program is affiliated with Michigan State University.

[1] MyMichigan Medical Center Midland was designed by architect Alden B. Dow and constructed amid wartime restrictions in 1943–44.

The first fifty years of the hospital's history is chronicled in the book, A Journey of Caring, by Dorthoy Langdon Yates.

MyMichigan Medical Center Midland is a secondary-level acute care hospital.