It proceeds north-north-west for 54 kilometres, crossing the Black Kei River, to reach Queenstown (town renamed Komani in February 2016).

At the junction with Barkly Street in Maletswai, the N6 makes a left turn and proceeds to cross the Orange River into the Free State as the General Hertzog Bridge.

[1] From the Orange River crossing at Maletswai, the N6 goes north-north-east for 34 kilometres to the town of Rouxville, where it meets the southern terminus of the R26.

[1] From Smithfield, the N6 continues north-north-west for 70 kilometres to the town of Reddersburg, where it is joined by the R717 from Edenburg in the southern suburbs before they split in the central area.

[1] Prior to 1970, the N6 began from King William's Town in the Buffalo City Metropolitan Municipality and proceeded through Stutterheim.