Under first head coach Robert "Peanut" Doak,[2] North Carolina State won the first game it played 57–45 over the Virginia Cavaliers on December 7, 1974, en route to an 11–4 final record.

In her first season as the head coach, Kay Yow led her squad to the quarterfinals of the 1976 National Women's Invitation Tournament.

On January 12, 1978, the Wolfpack beat the #1 Wayland Baptist Flying Queens 98–86 for its first ever win over a number one ranked team.

On February 18, 1988, Coach Yow defeated the Wake Forest Demon Deacons 62–61 to collect her 100th career ACC victory.

The Wolfpack captured its fourth of seven ACC tournament titles to date on March 4, 1991, by beating Clemson 84–61.

[4] On March 27, North Carolina State took the floor in Kansas City to take on the Louisiana Tech Lady Techsters, but the team ultimately fell 84–65.

NC State retired the first set of women's basketball jerseys in school history on February 13, 2000.

Genia Beasley, Trudi Lacey, Chasity Melvin, Linda Page, Andrea Stinson, Trena Trice, and Susan Yow each had her jersey retired.

Nine Wolfpack players, including Genia Beasley, Summer Erb, Trudi Lacey, Rhonda Mapp, Chasity Melvin, Linda Page, Andrea Stinson, Trena Trice and Susan Yow, were named to the ACC's 50th anniversary women's basketball team on September 25, 2002.

On February 5, 2007, she became just the sixth coach in Division I women's basketball history to win 700 games with a 68–51 victory over the Florida State Seminoles.

On March 18, 2007, Yow recorded her 650th win at NC State with an 84–52 defeat of the Robert Morris Colonials.

[7] In her legendary career at NC State, she won almost 700 games, guided her teams to 20 NCAA tournaments, advanced to the Sweet 16 eleven times, and recorded 29 winning seasons.

In his first season at NC State (2013–14), Moore led the Wolfpack to a 25–8 record, a fourth-place finish in the ACC standings, and an NCAA Tournament appearance.

After an 18-15 campaign in 2014-15 and a 20–11 season in 2015–16, Moore led the Wolfpack to the NCAA Tournament Round of 32 in 2016–17 with an impressive 23–9 record (12-4 ACC).

He was also named a Naismith Women's College Coach of the Year Semifinalist after authoring upsets of four top-15 teams throughout the season: No.

On December 3, 2020, the #8 NCSU women beat the #1 ranked South Carolina team in Columbia with a final score of 54–46.

In their semifinal game against the #3 seeded Georgia Tech Yellow Jackets, the team overcame a 10-point deficit in the 4th quarter to win by a final score of 66–61.

They were again a first seed in the 2022 NCAA tournament, defeating Longwood, Kansas State, and Notre Dame on the way to the Elite Eight.

This marked the first time that both the NC State men's and women's teams have made the Final Four in the same season.