NASA Extreme Environment Mission Operations, or NEEMO,[1] is a NASA analog mission that sends groups of astronauts, engineers and scientists to live in the Aquarius underwater laboratory, the world's only undersea research station, for up to three weeks at a time in preparation for future space exploration.

By living in the Aquarius habitat and working at the same depth on the ocean floor, NEEMO crews are able to remain underwater for the duration of their mission.

The underwater condition has the additional benefit of allowing NASA to "weight" the aquanauts to simulate different gravity environments.

[4] As part of the FIU Marine Education and Research Initiative, the Medina Aquarius Program is dedicated to the study and preservation of marine ecosystems worldwide and is enhancing the scope and impact of FIU on research, educational outreach, technology development, and professional training.

Additional EVAs will simulate working on the surface of an asteroid, and the use of the DeepWorker submersible as an underwater stand-in for the Multi-Mission Space Exploration Vehicle.