Nahal Issaron (Hebrew: נחל עשרון Naẖal Issaron) is a wadi and neolithic settlement in southern Negev, Israel.

It is located at the eastern edge of Ovda Valley, 35 kilometres (22 mi) north of the Gulf of Elat and 5 kilometres (3.1 mi) west of Arabah Rift valley.

[1] Excavations carried out by Avi Gopher and Nigel Goring-Morris in Nahal Issaron in 1980 uncovered remnants of an early pastoralist settlement belonging to the Pre-Pottery Neolithic B period.

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