It is bordered by Lugogo to the north, Nakawa to the northeast, Kiswa and Bugoloobi to the east, Muyenga to the southeast, Kisugu and Kabalagala to the south, Kibuli to the west and Kololo to the northwest.

The neighborhood is located approximately 6 kilometres (3.7 mi), by road, southeast of the central business district of the city.

However, as the population of Kampala has exploded in the 1990s and early 2000s, high-end businesses have moved into the area and raised its profile.

Namuwongo's proximity to high-end Kololo and Muyenga, as well as middle-class Nakawa and Bugoloobi, has ensured that it will not be mired into the low-end of the neighborhood spectrum.

Low land values arguably played a role in attracting big business to the neighborhood, at least in the beginning.